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Compounds were formulated with 10% DMSO and 10% Tween-80, and vortexed to obtain a uniform mixture

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This work was further supported by the Wellcome Trust (206194, 220540/Z/20/A), Cancer Research UK (CRUK) (C44943/A22536, A24430, A23441, A22536, A22534 and A22533), and multiple grants from the National Cancer Institute and NIH (including U24CA264007, U24CA210990, U24CA264032, U54CA274506, U01CA272610, U24CA264021, U24CA264010, U24CA264006, U24CA264028-01, P30CA008748, U24CA264009, U24CA264029, U24CA264024, U24CA264023 and U24CA264027)