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The peptide has also been investigated as a regulator of the sleep cycle, as it increases levels of melatonin and endogenous gonadotropic hormones (FSG, LG, prolactin), which play a role in reproductive function but naturally decline with age

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Preclinical work has reported a distinct selectivity profile, with growth hormone stimulation observed at concentrations that did not trigger ACTH or cortisol secretion, making it a useful tool for isolating growth hormone-specific signalling without activation of the hypothalamic-pituitary-adrenal axis

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