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First of all, ferroptosis may be impacted by the overexpression of genes related to iron metabolism, such as HO-1, caused by the activation of HIF-1α in hypoxic environments ( Figure 3 )

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Effects of diallyl sulfide and diallyl disulfide on cisplatin-induced changes in… [PMID: 8949992] Laboratory literature summary: Effects of diallyl sulfide and diallyl disulfide on cisplatin-induced changes in glutathione and glutathione-S-transferase activity