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We further demonstrate that a senolytic FOXO4-D-retro-inverso-isoform peptide (FOXO4-DRI) promotes apoptosis and decreases G0/G1 phase cells in pro-senescence models of keloid organ cultures and fibroblasts, accompanied with p53-pS15 nuclear exclusion

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And the formulation that carried GHK-Cu into controlled human testing under a pharmaceutical generic name was a topical gel , not an injection — the one time the compound was developed with regulatory intent, the route chosen was the skin