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The etiology of these masses is likely due to the presence of inflammation known to slow lymphatic pumping leaving more pre-lymph fluid in the ECM, inducing adipogenesis, as lymph (even pre-lymph) makes fat grow

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Son taux diminue avec l’âge (surtout à partir de 45-50 ans) et lors de l’augmentation des besoins de défense de l’organisme (immunité, détoxification hépatique, défenses antioxydantes…)