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Glutamate dehydrogenase 1 - Wikipedia

Complementing these disease-specific examples, epigenome-wide studies in type 1 diabetes (T1D) have demonstrated methylation abnormalities in immune effector cells (CD4+ T cells, B cells and monocytes), underscoring that immune epigenomes are broadly sensitive to both inflammatory context and metabolic state (112,113)

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Interestingly, both compounds showed the ability to improve kidney damage by decreasing creatinine and urea nitrogen levels compared to the group of mice with long‐term hyperuricemia, while febuxostat showed no significant effect [56]