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Compounds such as sulforaphane and bardoxolone function as Nrf2 activators, enhancing antioxidant capacity and increasing GPX4 activity, which leads to reduced lipid peroxidation and prevents ferroptosis (71,72)

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2.8 CCK-8 assay HUVECs were evenly seeded into 96-well plates at a density of 1 × 10^4 cells per well, with a culture medium volume of 100 µL per well