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Conventional supportive treatment—typically comprising intravenous fluids, antiemetics, antibiotics such as ceftriaxone-tazobactam, and nonsteroidal anti-inflammatory drugs like meloxicam—does not significantly reduce nitric oxide (NOx) and MDA levels or improve glutathione S-transferase (GST) activity

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these metabolic changes are associated with a 50% reduction in cardiac adenosine triphosphate (ATP) levels and impaired cardiac function 6

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