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However, loss-of-function mutations in TREX1 are clearly pathogenic in monogenic diseases such as Aicardi-Goutières Syndrome, but their contribution to complex autoimmune diseases such as SLE still requires more population genetic studies

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BPC-157 is widely studied in tissue repair (tendon, ligament, muscle, bone), gastrointestinal protection (ulcers, IBD, leaky gut), neuroprotection, cardiovascular research, and wound healing