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First, although we identified STAT1 as a key transcriptional regulator of microglial GLS1 in PND, we cannot exclude the contribution of other inflammation-related transcription factors, including NF‑κB and c‑Myc, to pathological GLS1 upregulation

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Potential therapeutic strategies for the treatment of human diseases Small molecule inhibitors or inducers targeting ferroptosis have been widely used in preclinical practice and have demonstrated potential in treating diseases by modulating ferroptosis