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Les radicaux libres sont des atomes ou des groupes d'atomes contenant un nombre impair d'électrons

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The authors showed that the addition of high-dose (5 g) vitamin C to EDTA chelation solutions induced acute prooxidant effect, as monitored by lipid, protein, and DNA oxidative markers, but that long treatment (e.g., multiple sessions of EDTA chelation therapy) protected against oxidative damage, despite the presence of vitamin C