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Acute studies: Clinical investigations involving ischemic stroke have used short treatment courses of approximately 5–10 days , with larger total daily intranasal amounts selected according to stroke severity.⁴ Short repeated-exposure studies: Animal studies commonly administer Semax daily for approximately 10–14 days while evaluating behavior, learning, stress response, or neurochemical changes.¹⁵ Longer developmental models: Some experiments have administered Semax daily over roughly two weeks during defined postnatal periods and assessed behavioral or metabolic outcomes later in development.¹ Evidence Limitations Semax has a broader research history than many experimental peptides, but the evidence has important limitations

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