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doi: 10.1016/j.metabol.2006.01.003 [DOI] [PubMed] [Google Scholar] 9.Unger J

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Our group recently described that a genetic disruption of the xCT subunit using CRISPR-Cas9 inhibits protein synthesis and proliferation in vitro ( 14 C-cystine transport assay in xCT knockout (xCT-KO) cells revealed this transporter as unique and indispensible for cystine uptake, as a complete abolishment of cystine transport has been observed