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Topical side effects: - Mild scalp redness or irritation (5 to 10% of users), typically resolves within days - Temporary shedding increase during the first 2 weeks (adjustment phase) - Contact dermatitis in rare cases, usually from other ingredients in the serum formulation Injectable side effects: - Injection site redness or swelling (resolves within hours) - Mild headache in the first week of use (uncommon) - See the GHK-Cu injection dosage guide for full safety data The copper uglies explained: This is the most important side effect to understand