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Curcumin suppresses NF-κB, MAPK, and JAK/STAT signaling, downregulating pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) while enhancing anti-inflammatory IL-10

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Key Takeaway: While natural production dips starting in the 20s, the 30s and 40s represent a critical window for introducing glutathione to support cellular resilience and long-term vitality